Patrick Bouvier Kennedy (August 7, 1963 – August 9, 1963) was the younger son of United States President John F. Kennedy and First Lady Jacqueline Bouvier Kennedy. He was born five and a half weeks prematurely by emergency caesarean section at the Otis Air Force Base Hospital, with a birth weight of 4 lb, 10 1/2 oz (1.863 kg), and was transferred to Boston Children's Hospital where he died two days later of hyaline membrane disease. His obituary in The New York Times pointed out that, at that time, all that could be done "for a victim of hyaline membrane disease is to monitor the infant's blood chemistry and to try to keep it near normal levels. Thus, the battle for the Kennedy baby was lost only because medical science has not yet advanced far enough to accomplish as quickly as necessary what the body can do by itself in its own time".
The death of their son devastated the First Couple. Jacqueline found it difficult to cope in the weeks that followed the tragedy, and the President and his mother-in-law, Janet Auchincloss, feared she would have a nervous breakdown as a result. It brought the President and his wife closer than they had ever been before and only he brought her through the grief they shared. However, just under four months later, Jacqueline would lose her husband too.